<?xml version=“1.0” encoding=“UTF-8”?> <MedicationDispense xmlns=“hl7.org/fhir”>

  <id value="meddisp0306"/>
  <meta>
  <security>
    <system value="http://terminology.hl7.org/CodeSystem/v3-ActReason"/>
    <code value="HTEST"/>
    <display value="test health data"/>
  </security>
</meta>
<contained>
      <Medication>
          <id value="med0303"/>
          <code>
              <coding>
                  <system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
                  <code value="1594660"/>
                  <display value="Alemtuzumab 10mg/ml (Lemtrada)"/>
              </coding>
          </code>
      </Medication>
  </contained>
  <status value="in-progress"/>
  <medicationReference>
      <!--   Linked to a RESOURCE Medication   -->
      <reference value="#med0303"/>
      <display value="Alemtuzumab 10mg/ml (Lemtrada)"/>
  </medicationReference>
  <subject>
      <reference value="Patient/pat1"/>
      <display value="Donald Duck"/>
  </subject>
  <performer>
      <actor>
          <reference value="Practitioner/f006"/>
      </actor>
  </performer>
  <authorizingPrescription>
      <reference value="MedicationRequest/medrx0317"/>
  </authorizingPrescription>
  <type>
      <coding>
          <system value="http://terminology.hl7.org/CodeSystem/v3-ActCode"/>
          <code value="DF"/>
          <display value="Daily Fill"/>
      </coding>
  </type>
  <quantity>
      <value value="5"/>
      <system value="http://snomed.info/sct"/>
      <code value="415818006"/>
  </quantity>
  <daysSupply>
      <value value="7"/>
      <unit value="Day"/>
      <system value="http://unitsofmeasure.org"/>
      <code value="d"/>
  </daysSupply>
  <whenPrepared value="2015-01-15T10:20:00Z"/>
  <dosageInstruction>
      <sequence value="1"/>
      <text value="Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk"/>
      <additionalInstruction>
          <text value="Rapidly increase dose until tolerated"/>
      </additionalInstruction>
      <additionalInstruction>
          <text value="Administer on alternate days"/>
      </additionalInstruction>
      <timing>
          <repeat>
              <duration value="12"/>
              <durationUnit value="wk"/>
              <frequency value="3"/>
              <period value="1"/>
              <periodUnit value="wk"/>
          </repeat>
      </timing>
      <route>
          <coding>
              <system value="http://snomed.info/sct"/>
              <code value="47625008"/>
              <display value="Intravenous route (qualifier value)"/>
          </coding>
      </route>
      <method>
          <coding>
              <system value="http://snomed.info/sct"/>
              <code value="422145002"/>
              <display value="Inject - dosing instruction imperative (qualifier value)"/>
          </coding>
      </method>
      <doseAndRate>
          <type>
              <coding>
                  <system value="http://terminology.hl7.org/CodeSystem/dose-rate-type"/>
                  <code value="calculated"/>
                  <display value="Calculated"/>
              </coding>
          </type>
          <doseQuantity>
              <value value="3"/>
              <unit value="mg"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="mg"/>
          </doseQuantity>
      </doseAndRate>

  </dosageInstruction>
  <dosageInstruction>
      <sequence value="2"/>
      <text value="Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk"/>
      <additionalInstruction>
          <text value="Rapidly increase dose until tolerated"/>
      </additionalInstruction>
      <additionalInstruction>
          <text value="Administer on alternate days"/>
      </additionalInstruction>
      <timing>
          <repeat>
              <duration value="12"/>
              <durationUnit value="wk"/>
              <frequency value="3"/>
              <period value="1"/>
              <periodUnit value="wk"/>
          </repeat>
      </timing>
      <route>
          <coding>
              <system value="http://snomed.info/sct"/>
              <code value="47625008"/>
              <display value="Intravenous route (qualifier value)"/>
          </coding>
      </route>
      <method>
          <coding>
              <system value="http://snomed.info/sct"/>
              <code value="422145002"/>
              <display value="Inject - dosing instruction imperative (qualifier value)"/>
          </coding>
      </method>
      <doseAndRate>
          <type>
              <coding>
                  <system value="http://terminology.hl7.org/CodeSystem/dose-rate-type"/>
                  <code value="calculated"/>
                  <display value="Calculated"/>
              </coding>
          </type>
          <doseQuantity>
              <value value="10"/>
              <unit value="mg"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="mg"/>
          </doseQuantity>
      </doseAndRate>

  </dosageInstruction>  
  <dosageInstruction>
      <sequence value="3"/>
      <text value="Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk"/>
      <additionalInstruction>
          <text value="Rapidly increase dose until tolerated"/>
      </additionalInstruction>
      <additionalInstruction>
          <text value="Administer on alternate days"/>
      </additionalInstruction>
      <timing>
          <repeat>
              <duration value="12"/>
              <durationUnit value="wk"/>
              <frequency value="3"/>
              <period value="1"/>
              <periodUnit value="wk"/>
          </repeat>
      </timing>
      <route>
          <coding>
              <system value="http://snomed.info/sct"/>
              <code value="47625008"/>
              <display value="Intravenous route (qualifier value)"/>
          </coding>
      </route>
      <method>
          <coding>
              <system value="http://snomed.info/sct"/>
              <code value="422145002"/>
              <display value="Inject - dosing instruction imperative (qualifier value)"/>
          </coding>
      </method>
      <doseAndRate>
          <type>
              <coding>
                  <system value="http://terminology.hl7.org/CodeSystem/dose-rate-type"/>
                  <code value="calculated"/>
                  <display value="Calculated"/>
              </coding>
          </type>
          <doseQuantity>
              <value value="30"/>
              <unit value="mg"/>
              <system value="http://unitsofmeasure.org"/>
              <code value="mg"/>
          </doseQuantity>
      </doseAndRate>
  </dosageInstruction>

</MedicationDispense>