<?xml version=“1.0” encoding=“UTF-8”?> <MedicationRequest xmlns=“hl7.org/fhir”>
<id value="medrx0317"/> <meta> <security> <system value="http://terminology.hl7.org/CodeSystem/v3-ActReason"/> <code value="HTEST"/> <display value="test health data"/> </security> </meta> <contained> <Medication> <id value="med0303"/> <code> <coding> <system value="http://www.nlm.nih.gov/research/umls/rxnorm"/> <code value="1594660"/> <display value="Alemtuzumab 10mg/ml (Lemtrada)"/> </coding> </code> </Medication> </contained> <identifier> <use value="official"/> <system value="http://www.bmc.nl/portal/prescriptions"/> <value value="12345689"/> </identifier> <status value="completed"/> <intent value="order"/> <medicationReference> <reference value="#med0303"/> </medicationReference> <subject> <!-- Linked to the resource patient who needs the medication --> <reference value="Patient/pat1"/> <display value="Donald Duck"/> </subject> <authoredOn value="2015-01-15"/> <requester> <reference value="Practitioner/f007"/> <display value="Patrick Pump"/> </requester> <reasonCode> <coding> <system value="http://snomed.info/sct"/> <code value="92814006"/> <display value="Chronic Lymphoid Leukemia (disorder)"/> </coding> </reasonCode> <dosageInstruction> <sequence value="1"/> <text value="Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk"/> <additionalInstruction> <text value="Rapidly increase dose until tolerated"/> </additionalInstruction> <additionalInstruction> <text value="Administer on alternate days"/> </additionalInstruction> <timing> <repeat> <duration value="12"/> <durationUnit value="wk"/> <frequency value="3"/> <period value="1"/> <periodUnit value="wk"/> </repeat> </timing> <route> <coding> <system value="http://snomed.info/sct"/> <code value="47625008"/> <display value="Intravenous route (qualifier value)"/> </coding> </route> <method> <coding> <system value="http://snomed.info/sct"/> <code value="422145002"/> <display value="Inject - dosing instruction imperative (qualifier value)"/> </coding> </method> <doseAndRate> <type> <coding> <system value="http://terminology.hl7.org/CodeSystem/dose-rate-type"/> <code value="ordered"/> <display value="Ordered"/> </coding> </type> <doseQuantity> <value value="3"/> <unit value="mg"/> <system value="http://unitsofmeasure.org"/> <code value="mg"/> </doseQuantity> </doseAndRate> </dosageInstruction> <dosageInstruction> <sequence value="2"/> <text value="Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk"/> <additionalInstruction> <text value="Rapidly increase dose until tolerated"/> </additionalInstruction> <additionalInstruction> <text value="Administer on alternate days"/> </additionalInstruction> <timing> <repeat> <duration value="12"/> <durationUnit value="wk"/> <frequency value="3"/> <period value="1"/> <periodUnit value="wk"/> </repeat> </timing> <route> <coding> <system value="http://snomed.info/sct"/> <code value="47625008"/> <display value="Intravenous route (qualifier value)"/> </coding> </route> <method> <coding> <system value="http://snomed.info/sct"/> <code value="422145002"/> <display value="Inject - dosing instruction imperative (qualifier value)"/> </coding> </method> <doseAndRate> <type> <coding> <system value="http://terminology.hl7.org/CodeSystem/dose-rate-type"/> <code value="ordered"/> <display value="Ordered"/> </coding> </type> <doseQuantity> <value value="10"/> <unit value="mg"/> <system value="http://unitsofmeasure.org"/> <code value="mg"/> </doseQuantity> </doseAndRate> </dosageInstruction> <dosageInstruction> <sequence value="3"/> <text value="Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk"/> <additionalInstruction> <text value="Rapidly increase dose until tolerated"/> </additionalInstruction> <additionalInstruction> <text value="Administer on alternate days"/> </additionalInstruction> <timing> <repeat> <duration value="12"/> <durationUnit value="wk"/> <frequency value="3"/> <period value="1"/> <periodUnit value="wk"/> </repeat> </timing> <route> <coding> <system value="http://snomed.info/sct"/> <code value="47625008"/> <display value="Intravenous route (qualifier value)"/> </coding> </route> <method> <coding> <system value="http://snomed.info/sct"/> <code value="422145002"/> <display value="Inject - dosing instruction imperative (qualifier value)"/> </coding> </method> <doseAndRate> <type> <coding> <system value="http://terminology.hl7.org/CodeSystem/dose-rate-type"/> <code value="ordered"/> <display value="Ordered"/> </coding> </type> <doseQuantity> <value value="30"/> <unit value="mg"/> <system value="http://unitsofmeasure.org"/> <code value="mg"/> </doseQuantity> </doseAndRate> </dosageInstruction>
</MedicationRequest>