{

"resourceType": "PlanDefinition",
"id": "KDN5",
"contained": [
  {
    "resourceType": "ActivityDefinition",
    "id": "1111",
    "status": "draft",
    "productCodeableConcept": {
      "coding": [
        {
          "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
          "code": "12574",
          "display": "gemcitabine"
        }
      ],
      "text": "gemcitabine"
    },
    "dosage": [
      {
        "text": "1250 mg/m² IV over 30 minutes",
        "timing": {
          "repeat": {
            "duration": 30,
            "durationUnit": "min"
          }
        },
        "route": {
          "text": "IV"
        },
        "doseAndRate": [
          {
            "type": {
              "coding": [
                {
                  "system": "http://terminology.hl7.org/CodeSystem/dose-rate-type",
                  "code": "ordered",
                  "display": "Ordered"
                }
              ]
            },
            "doseQuantity": {
              "value": 1250,
              "unit": "mg/m²"
            }
          }
        ]
      }
    ]
  },
  {
    "resourceType": "ActivityDefinition",
    "id": "2222",
    "status": "draft",
    "productCodeableConcept": {
      "coding": [
        {
          "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
          "code": "40048",
          "display": "Carboplatin"
        }
      ],
      "text": "CARBOplatin"
    },
    "dosage": [
      {
        "text": "AUC 5 IV over 30 minutes",
        "timing": {
          "repeat": {
            "duration": 30,
            "durationUnit": "min"
          }
        },
        "route": {
          "text": "IV"
        },
        "doseAndRate": [
          {
            "type": {
              "coding": [
                {
                  "system": "http://terminology.hl7.org/CodeSystem/dose-rate-type",
                  "code": "ordered",
                  "display": "Ordered"
                }
              ]
            },
            "doseQuantity": {
              "extension": [
                {
                  "url": "http://example.org/fhir/AUC-dose",
                  "valueInteger": 5
                }
              ]
            }
          }
        ]
      }
    ]
  }
],
"identifier": [
  {
    "system": "http://example.org/ordertemplates",
    "value": "KDN5"
  }
],
"version": "1",
"title": "Gemcitabine/CARBOplatin",
"type": {
  "text": "Chemotherapy Order Template"
},
"status": "draft",
"experimental": true,
"publisher": "National Comprehensive Cancer Network, Inc.",
"useContext": [
  {
    "extension": [
      {
        "url": "http://hl7.org/fhir/StructureDefinition/usagecontext-group",
        "valueString": "A"
      }
    ],
    "code": {
      "system": "http://example.org/fhir/CodeSystem/indications",
      "code": "treamentSetting-or-diseaseStatus"
    },
    "valueCodeableConcept": {
      "text": "Metastatic"
    }
  },
  {
    "extension": [
      {
        "url": "http://hl7.org/fhir/StructureDefinition/usagecontext-group",
        "valueString": "A"
      }
    ],
    "code": {
      "system": "http://example.org/fhir/CodeSystem/indications",
      "code": "disease-or-histology"
    },
    "valueCodeableConcept": {
      "text": "Collecting Duct/Medullary Subtypes"
    }
  },
  {
    "extension": [
      {
        "url": "http://hl7.org/fhir/StructureDefinition/usagecontext-group",
        "valueString": "A"
      }
    ],
    "code": {
      "system": "http://terminology.hl7.org/CodeSystem/usage-context-type",
      "code": "focus"
    },
    "valueCodeableConcept": {
      "text": "Kidney Cancer"
    }
  },
  {
    "extension": [
      {
        "url": "http://hl7.org/fhir/StructureDefinition/usagecontext-group",
        "valueString": "B"
      }
    ],
    "code": {
      "system": "http://example.org/fhir/CodeSystem/indications",
      "code": "treatmentSetting-or-diseaseStatus"
    },
    "valueCodeableConcept": {
      "text": "Relapsed"
    }
  },
  {
    "extension": [
      {
        "url": "http://hl7.org/fhir/StructureDefinition/usagecontext-group",
        "valueString": "B"
      }
    ],
    "code": {
      "system": "http://example.org/fhir/CodeSystem/indications",
      "code": "disease-or-histology"
    },
    "valueCodeableConcept": {
      "text": "Collecting Duct/Medullary Subtypes"
    }
  },
  {
    "extension": [
      {
        "url": "http://hl7.org/fhir/StructureDefinition/usagecontext-group",
        "valueString": "B"
      }
    ],
    "code": {
      "system": "http://terminology.hl7.org/CodeSystem/usage-context-type",
      "code": "focus"
    },
    "valueCodeableConcept": {
      "text": "Kidney Cancer – Collecting Duct/Medullary Subtypes - Metastatic"
    }
  }
],
"copyright": "All rights reserved.",
"approvalDate": "2016-07-27",
"lastReviewDate": "2016-07-27",
"author": [
  {
    "name": "Lee Surprenant"
  }
],
"relatedArtifact": [
  {
    "type": "derived-from",
    "display": "NCCN Guidelines for Kidney Cancer. V.2.2016",
    "url": "http://www.example.org/professionals/physician_gls/PDF/kidney.pdf"
  },
  {
    "type": "citation",
    "_type": {
      "extension": [
        {
          "url": "http://example.org/fhir/regimenReferenceType",
          "valueCode": "a"
        }
      ]
    },
    "citation": "Oudard S, et al. J Urol. 2007;177(5):1698-702",
    "url": "http://www.ncbi.nlm.nih.gov/pubmed/17437788"
  }
],
"action": [
  {
    "selectionBehavior": "exactly-one",
    "action": [
      {
        "selectionBehavior": "all",
        "action": [
          {
            "groupingBehavior": "sentence-group",
            "selectionBehavior": "exactly-one",
            "action": [
              {
                "id": "cycle-definition-1",
                "textEquivalent": "21-day cycle for 6 cycles",
                "timingTiming": {
                  "repeat": {
                    "count": 6,
                    "duration": 21,
                    "durationUnit": "d"
                  }
                },
                "action": [
                  {
                    "id": "action-1",
                    "extension": [
                      {
                        "url": "http://hl7.org/fhir/StructureDefinition/timing-daysOfCycle",
                        "extension": [
                          {
                            "url": "day",
                            "valueInteger": 1
                          },
                          {
                            "url": "day",
                            "valueInteger": 8
                          }
                        ]
                      }
                    ],
                    "textEquivalent": "Gemcitabine 1250 mg/m² IV over 30 minutes on days 1 and 8",
                    "definitionCanonical": "#1111"
                  },
                  {
                    "id": "action-2",
                    "extension": [
                      {
                        "url": "http://hl7.org/fhir/StructureDefinition/timing-daysOfCycle",
                        "extension": [
                          {
                            "url": "day",
                            "valueInteger": 1
                          }
                        ]
                      }
                    ],
                    "textEquivalent": "CARBOplatin AUC 5 IV over 30 minutes on Day 1",
                    "relatedAction": [
                      {
                        "actionId": "action-1",
                        "relationship": "concurrent-with-start"
                      }
                    ],
                    "definitionCanonical": "#2222"
                  }
                ]
              }
            ]
          }
        ]
      }
    ]
  }
],
"meta": {
  "tag": [
    {
      "system": "http://terminology.hl7.org/CodeSystem/v3-ActReason",
      "code": "HTEST",
      "display": "test health data"
    }
  ]
}

}