<?xml version=“1.0” encoding=“UTF-8”?><DetectedIssue xmlns=“hl7.org/fhir”>

<id value="ddi"/>
<text>
  <status value="generated"/>
  <div xmlns="http://www.w3.org/1999/xhtml">
    <p><b>Severity: High</b> - Risk of internal bleeding</p>
    <p>Those who take acetaminophen along with the widely used blood-thinning drug warfarin may face the risk of serious internal bleeding. People on warfarin who take acetaminophen for at least seven days in a row should be closely watched for bleeding.</p>
    <ul>
      <li><a href="MedicationStatement/tylenol">500 mg Acetaminophen tablet 1/day, PRN since 2010</a></li>
      <li><a href="MedicationOrder/warfarin">Warfarin 1 MG TAB prescribed Jan. 5, 2014</a></li>
    </ul>
    <p>Mitigation: Jan 5, 2014 by Dr. Adam Careful: </p>
    <p>Asked patient to discontinue regular use of Tylenol and to consult with clinician if they need to resume to allow appropriate INR monitoring</p>
  </div>
</text>
<category>
  <coding>
    <system value="http://hl7.org/fhir/v3/ActCode"/>
    <code value="DRG"/>
    <display value="Drug Interaction Alert"/>
  </coding>
</category>
<severity value="high"/>
<implicated>
  <reference value="MedicationStatement/tylenol"/>
  <display value="500 mg Acetaminophen tablet 1/day, PRN since 2010"/>
</implicated>
<implicated>
  <reference value="MedicationOrder/warfarin"/>
  <display value="Warfarin 1 MG TAB prescribed Jan. 5, 2014"/>
</implicated>
<detail value="Risk of internal bleeding.  Those who take acetaminophen along with the widely used blood-thinning drug warfarin may face the risk of serious internal bleeding. People on warfarin who take acetaminophen for at least seven days in a row should be closely watched for bleeding."/>
<date value="2014-01-05"/>
<author>
  <reference value="Device/dsp"/>
</author>
<mitigation>
  <action>
    <coding>
      <system value="http://hl7.org/fhir/v3/ActCode"/>
      <code value="13"/>
      <display value="Stopped Concurrent Therapy"/>
    </coding>
    <text value="Asked patient to discontinue regular use of Tylenol and to consult with clinician if they need to resume to allow appropriate INR monitoring"/>
  </action>
  <date value="2014-01-05"/>
  <author>
    <reference value="Practitioner/example"/>
    <display value="Dr. Adam Careful"/>
  </author>
</mitigation>

</DetectedIssue>