%global __brp_check_rpaths %{nil} %global packname scINSIGHT %global packver 0.1.4 %global rlibdir /usr/local/lib/R/library Name: R-CRAN-%{packname} Version: 0.1.4 Release: 1%{?dist}%{?buildtag} Summary: Interpretation of Heterogeneous Single-Cell Gene Expression Data License: GPL-3 URL: https://cran.r-project.org/package=%{packname} Source0: %{url}&version=%{packver}#/%{packname}_%{packver}.tar.gz BuildRequires: R-devel Requires: R-core BuildRequires: R-methods BuildRequires: R-CRAN-Rcpp BuildRequires: R-CRAN-RANN BuildRequires: R-CRAN-igraph BuildRequires: R-parallel BuildRequires: R-stats BuildRequires: R-CRAN-stringr BuildRequires: R-CRAN-RcppArmadillo Requires: R-methods Requires: R-CRAN-Rcpp Requires: R-CRAN-RANN Requires: R-CRAN-igraph Requires: R-parallel Requires: R-stats Requires: R-CRAN-stringr %description We develop a novel matrix factorization tool named 'scINSIGHT' to jointly analyze multiple single-cell gene expression samples from biologically heterogeneous sources, such as different disease phases, treatment groups, or developmental stages. Given multiple gene expression samples from different biological conditions, 'scINSIGHT' simultaneously identifies common and condition-specific gene modules and quantify their expression levels in each sample in a lower-dimensional space. With the factorized results, the inferred expression levels and memberships of common gene modules can be used to cluster cells and detect cell identities, and the condition-specific gene modules can help compare functional differences in transcriptomes from distinct conditions. Please also see Qian K, Fu SW, Li HW, Li WV (2022) . %prep %setup -q -c -n %{packname} # fix end of executable files find -type f -executable -exec grep -Iq . {} \; -exec sed -i -e '$a\' {} \; # prevent binary stripping [ -d %{packname}/src ] && find %{packname}/src -type f -exec \ sed -i 's@/usr/bin/strip@/usr/bin/true@g' {} \; || true [ -d %{packname}/src ] && find %{packname}/src/Make* -type f -exec \ sed -i 's@-g0@@g' {} \; || true # don't allow local prefix in executable scripts find -type f -executable -exec sed -Ei 's@#!( )*/usr/local/bin@#!/usr/bin@g' {} \; %build %install mkdir -p %{buildroot}%{rlibdir} %{_bindir}/R CMD INSTALL -l %{buildroot}%{rlibdir} %{packname} test -d %{packname}/src && (cd %{packname}/src; rm -f *.o *.so) rm -f %{buildroot}%{rlibdir}/R.css # remove buildroot from installed files find %{buildroot}%{rlibdir} -type f -exec sed -i "s@%{buildroot}@@g" {} \; %files %{rlibdir}/%{packname}