doseComb_to_mat {crm12Comb} | R Documentation |
Step 1: convert dose combinations into matrix
doseComb_to_mat(doseComb, type)
doseComb |
Either a numeric matrix or a numeric vector or a numeric list. |
type |
A string. condition 1: detailed dose combinations are directly given in matrix -> type = "comb" dose combinations dose A dose B condition 2: directly given the number of levels for the two doses in vector -> type = "matrix" Step 2: get the 6 orderings |
outMat -> Either a list or a matrix. Note: each array refers to the index of drug combinations orderings)
Wages NA, Conaway MR. Specifications of a continual reassessment method design for phase I trials of combined drugs. Pharmaceutical statistics. 2013 Jul;12(4):217-24. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771354/