ExchangeableAmides {OrgMassSpecR} | R Documentation |
Determine the number of backbone amide hydrogens given a protein/peptide sequence. Used in hydrogen-deuterium exchange experiments.
ExchangeableAmides(sequence)
sequence |
character vector containing one or more amino acid sequences. |
The number of backbone amide hydrogens in an amino acid sequence is the number of residues, minus the number of prolines, minus 1.
A numeric vector containing the number of exchangeable hydrogens.
Nathan G. Dodder
ExchangeableAmides(c("VDVMCTA", "VSTPTL"))
## find the number of exchangeable amides for
## each peptide in a digest of human serum albumin
x <- Digest(example.sequence, enzyme = "pepsin", IAA = FALSE, missed = 4)
transform(x, exchange = ExchangeableAmides(x$peptide))