stop_rule_d1extended {ewoc} | R Documentation |
Generating a stop rule function for EWOC extended model
stop_rule_d1extended(step)
step |
an object from the class 'ewoc_d1extended'. |
The stop rule function is evaluated at each step of the trial. It can defined based on any information contained in the object 'step' that is the output from one of the functions ewoc_d1extended'.
a logical character indicating if the trial should be stopped or not.
## Not run:
DLT <- 0
dose <- 20
step_zero <- ewoc_d1extended(DLT ~ dose, type = 'discrete',
theta = 0.33, alpha = 0.25,
min_dose = 0, max_dose = 100,
dose_set = seq(0, 100, 20),
rho_prior = matrix(1, ncol = 2, nrow = 2),
rounding = "nearest")
stop_rule_d1extended(step_zero)
response_sim <- response_d1extended(rho = c(0.05, 0.95),
min_dose = 10, max_dose = 50)
sim <- ewoc_simulation(step_zero = step_zero,
n_sim = 2, sample_size = 30,
alpha_strategy = "conditional",
response_sim = response_sim,
stop_rule_sim = stop_rule_d1extended,
ncores = 1)
## End(Not run)