%global __brp_check_rpaths %{nil} %global packname phase1RMD %global packver 1.0.9 %global rlibdir /usr/local/lib/R/library Name: R-CRAN-%{packname} Version: 1.0.9 Release: 3%{?dist}%{?buildtag} Summary: Repeated Measurement Design for Phase I Clinical Trial License: GPL (>= 2) URL: https://cran.r-project.org/package=%{packname} Source0: %{url}&version=%{packver}#/%{packname}_%{packver}.tar.gz BuildRequires: R-devel >= 3.0.0 Requires: R-core >= 3.0.0 BuildArch: noarch BuildRequires: R-CRAN-coda BuildRequires: R-boot BuildRequires: R-CRAN-rjags BuildRequires: R-CRAN-mvtnorm BuildRequires: R-CRAN-ggplot2 BuildRequires: R-CRAN-arrayhelpers Requires: R-CRAN-coda Requires: R-boot Requires: R-CRAN-rjags Requires: R-CRAN-mvtnorm Requires: R-CRAN-ggplot2 Requires: R-CRAN-arrayhelpers %description Implements our Bayesian phase I repeated measurement design that accounts for multidimensional toxicity endpoints from multiple treatment cycles. The package also provides a novel design to account for both multidimensional toxicity endpoints and early-stage efficacy endpoints in the phase I design. For both designs, functions are provided to recommend the next dosage selection based on the data collected in the available patient cohorts and to simulate trial characteristics given design parameters. Yin, Jun, et al. (2017) . %prep %setup -q -c -n %{packname} find -type f -executable -exec grep -Iq . {} \; -exec sed -i -e '$a\' {} \; %build %install mkdir -p %{buildroot}%{rlibdir} %{_bindir}/R CMD INSTALL -l %{buildroot}%{rlibdir} %{packname} test -d %{packname}/src && (cd %{packname}/src; rm -f *.o *.so) rm -f %{buildroot}%{rlibdir}/R.css %files %{rlibdir}/%{packname}