optimal_multiple_generic {drugdevelopR} | R Documentation |
This function is only used for documentation generation.
optimal_multiple_generic(rho, alpha, n2min, n2max, stepn2, fixed)
rho |
correlation between the two endpoints |
alpha |
one-sided significance level/family-wise error rate |
n2min |
minimal total sample size in phase II, must be divisible by 3 |
n2max |
maximal total sample size in phase II, must be divisible by 3 |
stepn2 |
stepsize for the optimization over n2, must be divisible by 3 |
fixed |
assumed fixed treatment effect |
No return value