dat {BElikelihood} | R Documentation |
The dataset is a bioequivalence dataset from a fully repicated 2x4 crossover design with RTRT and TRTR as sequences. It is a subset of Example 4.4 in Chapter 4 of Patterson and Jones's book.
data(dat, package = 'BElikelihood')
A data frame with 176 observations (from 44 subjects) on 6 variables:
subject ID
RTRT or TRTR, where T and R stand for test and reference drugs, respectively
1 to 4 for crossover period
T or R stand for test and reference drugs, respectively
a pharmacokinetic parameter - the area under the blood/plasma concentration-time curve
a pharmacokinetic parameter - the peak concentration
Patterson S and Jones B (2023). Bioequivalence and Statistics in Clinical Pharmacology. Chapman Hall/CRC Press.
data(dat)