ceas-package {ceas}R Documentation

ceas: Cellular Energetics Analysis Software

Description

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Analysis and visualization of cellular energetics data from Agilent Seahorse XF96. Cellular energetics is how cells make, use, and distribute units of energy (primarily ATP). Measuring real-time cellular energetics is essential to understanding a tissue or cell’s bioenergetic state and fuel dependencies. The Seahorse machine measures a cell’s or matrix’s oxygen consumption rate (OCR) – a proxy of oxidative phosphorylation – and extracellular acidification rate – a proxy of glycolysis. This package offers flexible and fast analysis and plotting capabilities for such data using the methods described by Mookerjee et al. (2017) doi:10.1074/jbc.m116.774471.

Author(s)

Maintainer: Rachel House rachel.house@vai.org (ORCID)

Authors:

Other contributors:

See Also

Useful links:


[Package ceas version 1.0.0 Index]