dose.survival {DTAT} | R Documentation |
Constructs a Surv
object from a dose-escalation
experiment, using interval-censoring constructs of type='interval2'
.
dose.survival(de)
de |
A data frame describing a dose-titration study |
A Surv
object of type='interval2'
David C. Norris
CV <- 0.7; mean_mtd <- 1.0
shape <- CV^-2; scale <- mean_mtd/shape
trial <- new("DE", doses=0.25 * 1.4^(0:6),
MTDi=rgamma(24, shape=shape, scale=scale),
units="mg")
trial <- titration(trial, periods=10)
dose.survival(trial@data)