NextBestMTD-class {crmPack} | R Documentation |
The class with the input for finding the next best MTD estimate
target
the target toxicity probability
derive
the function which derives from the input, a vector of
posterior MTD samples called mtdSamples
, the final next best MTD
estimate.
# In the example below the MTD is defined as the dose for which prob(DLE)=0.33 and
# we will use the 25th quantile of the posterior of MTD as our next best dose.
mtdNextBest <- NextBestMTD(target=0.33,
derive=
function(mtdSamples){
quantile(mtdSamples, probs=0.25)
})