ctrdata-registers {ctrdata} | R Documentation |
Registers of clinical trials from which protocol- and result-related information can be retrieved and analysed with package ctrdata, last updated 2024-11-10.
EUCTR: The EU Clinical Trials Register contains more than 44,200 clinical trials (at least one investigational medicinal product, IMP; in the European Union and beyond; no new trials, but results for contained trials continue to be added)
CTIS: The EU Clinical Trials Information System started in January 2023 for new clinical trials. It includes more than 7,300 publicly accessible trials. How to automatically get the CTIS search query URL: here
CTGOV2: ClinicalTrials.gov includes more than 515,000 interventional and observational studies
ISRCTN: The ISRCTN Registry includes more than 25,500 interventional and observational health studies
CTGOV was retired on 2024-06-25; ctrdata
subsequently translates CTGOV
queries to CTGOV2 queries. The new website (CTGOV2) can be used with ctrdata
since 2023-08-27. CTIS was relaunched on 2024-06-17, changing the data
structure and search syntax, to which ctrdata
was updated. CTIS can be used
with ctrdata
since 2023-03-25. More information on changes:
here.
Material | EUCTR | CTGOV2 | ISRCTN | CTIS |
Home page | link | link | link | link |
About | link | link | link | link |
Terms & conditions, disclaimer | link | link | link | link |
How to search | link | link | link | link |
Search interface | link | link | link | link |
Expert / advanced search | link | link | link | link |
Glossary | link | link | link | |
FAQ, caveats, issues | link | link | link | link |
Definitions | link | link | link | link |
Example* | link | link | link | link |
*The example is an expert search for interventional trials primarily with neonates, investigating infectious conditions. It shows that searches in registers may not be sufficient to identify the sought trials:
The CTGOV2 search retrieves trials conducted exclusively with neonates.
EUCTR retrieves trials with neonates, but not only those exclusively in neonates.
ISRCTN retrieves studies with interventions other than medicines.
CTIS retrieves trials that mention the words neonates and infection.
To address this, trials can be retrieved with ctrLoadQueryIntoDb into a database collection and in a second step can be selected, based on values of relevant fields of all retrieved trial information, for example:
EUCTR field f115_children_211years
for age criteria
ISRCTN field interventions.intervention.interventionType
for type of study
CTIS fields ageGroup
and authorizedApplication.authorizedPartI.medicalConditions.medicalCondition
ctrdata
helps identifying fields with function dbGetFieldsIntoDf.
Ralf Herold ralf.herold@mailbox.org