%global __brp_check_rpaths %{nil} %global __requires_exclude ^libmpi %global packname strata.MaxCombo %global packver 0.0.1 %global rlibdir /usr/local/lib/R/library Name: R-CRAN-%{packname} Version: 0.0.1 Release: 1%{?dist}%{?buildtag} Summary: Stratified Max-Combo Test License: GPL-2 URL: https://cran.r-project.org/package=%{packname} Source0: %{url}&version=%{packver}#/%{packname}_%{packver}.tar.gz BuildRequires: R-devel >= 3.5.0 Requires: R-core >= 3.5.0 BuildArch: noarch BuildRequires: R-CRAN-mvtnorm Requires: R-CRAN-mvtnorm %description Non-proportional hazard (NPH) is commonly observed in immuno-oncology studies, where the survival curves of the treatment and control groups show delayed separation. To properly account for NPH, several statistical methods have been developed. One such method is Max-Combo test, which is a straightforward and flexible hypothesis testing method that can simultaneously test for constant, early, middle, and late treatment effects. However, the majority of the Max-Combo test performed in clinical studies are unstratified, ignoring the important prognostic stratification factors. To fill this gap, we have developed an R package for stratified Max-Combo testing that accounts for stratified baseline factors. Our package explores various methods for calculating combined test statistics, estimating joint distributions, and determining the p-values. %prep %setup -q -c -n %{packname} # fix end of executable files find -type f -executable -exec grep -Iq . {} \; -exec sed -i -e '$a\' {} \; # prevent binary stripping [ -d %{packname}/src ] && find %{packname}/src -type f -exec \ sed -i 's@/usr/bin/strip@/usr/bin/true@g' {} \; || true [ -d %{packname}/src ] && find %{packname}/src/Make* -type f -exec \ sed -i 's@-g0@@g' {} \; || true # don't allow local prefix in executable scripts find -type f -executable -exec sed -Ei 's@#!( )*/usr/local/bin@#!/usr/bin@g' {} \; %build %install mkdir -p %{buildroot}%{rlibdir} %{_bindir}/R CMD INSTALL -l %{buildroot}%{rlibdir} %{packname} test -d %{packname}/src && (cd %{packname}/src; rm -f *.o *.so) rm -f %{buildroot}%{rlibdir}/R.css # remove buildroot from installed files find %{buildroot}%{rlibdir} -type f -exec sed -i "s@%{buildroot}@@g" {} \; %files %{rlibdir}/%{packname}