optimal_bias_generic {drugdevelopR} | R Documentation |
Generic function for optimizing drug development programs with bias adjustment
Description
Generic function for optimizing drug development programs with bias adjustment
Usage
optimal_bias_generic(
adj = "both",
lambdamin = NULL,
lambdamax = NULL,
steplambda = NULL,
alphaCImin = NULL,
alphaCImax = NULL,
stepalphaCI = NULL
)
Arguments
adj |
choose type of adjustment: |
lambdamin |
minimal multiplicative adjustment parameter lambda (i.e. use estimate with a retention factor) |
lambdamax |
maximal multiplicative adjustment parameter lambda (i.e. use estimate with a retention factor) |
steplambda |
stepsize for the adjustment parameter lambda |
alphaCImin |
minimal additive adjustment parameter alphaCI (i.e. adjust the lower bound of the one-sided confidence interval) |
alphaCImax |
maximal additive adjustment parameter alphaCI (i.e. adjust the lower bound of the one-sided confidence interval) |
stepalphaCI |
stepsize for alphaCI |