%global __brp_check_rpaths %{nil} %global __requires_exclude ^libmpi %global packname drugdevelopR %global packver 1.0.1 %global rlibdir /usr/local/lib/R/library Name: R-CRAN-%{packname} Version: 1.0.1 Release: 1%{?dist}%{?buildtag} Summary: Utility-Based Optimal Phase II/III Drug Development Planning License: MIT + file LICENSE URL: https://cran.r-project.org/package=%{packname} Source0: %{url}&version=%{packver}#/%{packname}_%{packver}.tar.gz BuildRequires: R-devel >= 3.5.0 Requires: R-core >= 3.5.0 BuildArch: noarch BuildRequires: R-CRAN-doParallel BuildRequires: R-parallel BuildRequires: R-CRAN-foreach BuildRequires: R-CRAN-iterators BuildRequires: R-CRAN-mvtnorm BuildRequires: R-CRAN-cubature BuildRequires: R-CRAN-msm BuildRequires: R-CRAN-MASS BuildRequires: R-stats BuildRequires: R-CRAN-progressr Requires: R-CRAN-doParallel Requires: R-parallel Requires: R-CRAN-foreach Requires: R-CRAN-iterators Requires: R-CRAN-mvtnorm Requires: R-CRAN-cubature Requires: R-CRAN-msm Requires: R-CRAN-MASS Requires: R-stats Requires: R-CRAN-progressr %description Plan optimal sample size allocation and go/no-go decision rules for phase II/III drug development programs with time-to-event, binary or normally distributed endpoints when assuming fixed treatment effects or a prior distribution for the treatment effect, using methods from Kirchner et al. (2016) and Preussler (2020). Optimal is in the sense of maximal expected utility, where the utility is a function taking into account the expected cost and benefit of the program. It is possible to extend to more complex settings with bias correction (Preussler S et al. (2020) ), multiple phase III trials (Preussler et al. (2019) ), multi-arm trials (Preussler et al. (2019) ), and multiple endpoints (Kieser et al. (2018) ). %prep %setup -q -c -n %{packname} # fix end of executable files find -type f -executable -exec grep -Iq . {} \; -exec sed -i -e '$a\' {} \; # prevent binary stripping [ -d %{packname}/src ] && find %{packname}/src -type f -exec \ sed -i 's@/usr/bin/strip@/usr/bin/true@g' {} \; || true [ -d %{packname}/src ] && find %{packname}/src/Make* -type f -exec \ sed -i 's@-g0@@g' {} \; || true # don't allow local prefix in executable scripts find -type f -executable -exec sed -Ei 's@#!( )*/usr/local/bin@#!/usr/bin@g' {} \; %build %install mkdir -p %{buildroot}%{rlibdir} %{_bindir}/R CMD INSTALL -l %{buildroot}%{rlibdir} %{packname} test -d %{packname}/src && (cd %{packname}/src; rm -f *.o *.so) rm -f %{buildroot}%{rlibdir}/R.css # remove buildroot from installed files find %{buildroot}%{rlibdir} -type f -exec sed -i "s@%{buildroot}@@g" {} \; %files %{rlibdir}/%{packname}