%global __brp_check_rpaths %{nil} %global packname diffEnrich %global packver 0.1.2 %global rlibdir /usr/local/lib/R/library Name: R-CRAN-%{packname} Version: 0.1.2 Release: 1%{?dist}%{?buildtag} Summary: Given a List of Gene Symbols, Performs Differential Enrichment Analysis License: GPL-2 URL: https://cran.r-project.org/package=%{packname} Source0: %{url}&version=%{packver}#/%{packname}_%{packver}.tar.gz BuildRequires: R-devel >= 2.10 Requires: R-core >= 2.10 BuildArch: noarch BuildRequires: R-CRAN-dplyr BuildRequires: R-CRAN-ggplot2 BuildRequires: R-CRAN-here BuildRequires: R-stats BuildRequires: R-CRAN-rlang BuildRequires: R-CRAN-stringr BuildRequires: R-CRAN-reshape2 BuildRequires: R-CRAN-ggnewscale Requires: R-CRAN-dplyr Requires: R-CRAN-ggplot2 Requires: R-CRAN-here Requires: R-stats Requires: R-CRAN-rlang Requires: R-CRAN-stringr Requires: R-CRAN-reshape2 Requires: R-CRAN-ggnewscale %description Compare functional enrichment between two experimentally-derived groups of genes or proteins (Peterson, DR., et al.(2018)) . Given a list of gene symbols, 'diffEnrich' will perform differential enrichment analysis using the Kyoto Encyclopedia of Genes and Genomes (KEGG) REST API. This package provides a number of functions that are intended to be used in a pipeline. Briefly, the user provides a KEGG formatted species id for either human, mouse or rat, and the package will download and clean species specific ENTREZ gene IDs and map them to their respective KEGG pathways by accessing KEGG's REST API. KEGG's API is used to guarantee the most up-to-date pathway data from KEGG. Next, the user will identify significantly enriched pathways from two gene sets, and finally, the user will identify pathways that are differentially enriched between the two gene sets. In addition to the analysis pipeline, this package also provides a plotting function. %prep %setup -q -c -n %{packname} # fix end of executable files find -type f -executable -exec grep -Iq . {} \; -exec sed -i -e '$a\' {} \; # prevent binary stripping [ -d %{packname}/src ] && find %{packname}/src -type f -exec \ sed -i 's@/usr/bin/strip@/usr/bin/true@g' {} \; || true [ -d %{packname}/src ] && find %{packname}/src/Make* -type f -exec \ sed -i 's@-g0@@g' {} \; || true # don't allow local prefix in executable scripts find -type f -executable -exec sed -Ei 's@#!( )*/usr/local/bin@#!/usr/bin@g' {} \; %build %install mkdir -p %{buildroot}%{rlibdir} %{_bindir}/R CMD INSTALL -l %{buildroot}%{rlibdir} %{packname} test -d %{packname}/src && (cd %{packname}/src; rm -f *.o *.so) rm -f %{buildroot}%{rlibdir}/R.css # remove buildroot from installed files find %{buildroot}%{rlibdir} -type f -exec sed -i "s@%{buildroot}@@g" {} \; %files %{rlibdir}/%{packname}