apply_duration_scale {PKPDsim} | R Documentation |
Apply infusion duration scale to a regimen
Description
E.g. see Centanni et al. Clin Pharmacokinet 2024. An estimated scaling factor for the length of the infusion was applied there in a model for vincristine. This is likely most relevant for very short infusions.
Usage
apply_duration_scale(
regimen,
duration_scale = NULL,
parameters = NULL,
cmt_mapping = NULL
)
Arguments
regimen |
PKPDsim regimen |
duration_scale |
infusion length scale. |
parameters |
parameter list, required if the duration scale is specified as a parameter. |
cmt_mapping |
map of administration types to compartments, e.g.
|
Details
Implementation is similar to handling of lagtime
, i.e. the regimen that is the
input for the simulation function is updated.
Value
Original regimen with infusion lengths scaled by a factor
[Package PKPDsim version 1.4.0 Index]