BMT {R4HCR} | R Documentation |
Bone Marrow Transplantation.
Description
A simplified version of the data set printed in Klein and Moeschberger, 2003. Briefly, these data are from a study of 137 patients with acute myelocytic leukemia (AML) or acute lymphoblastic leukemia (ALL) aged 7 to 52 from four centres. Failure time is defined as the time (in days) to relapse or death.
Usage
BMT
Format
A data frame with 137 observations on the following 3 variables.
group
Categorisation of the patients' Leukemia (
ALL
= Acute Lymphoblastic Leukemia,AML-High Risk
= High risk Acute Myelocytic Leukemia,AML-Low Risk
= Low risk Acute Myelocytic Leukemia).time
Failure time, defined as time (in days) to relapse or death.
status
Disease-free survival indicator (
1
= Dead or Relapsed,0
= Alive Disease Free).
Details
Bone marrow transplants are a standard treatment for acute leukemia.Recovery following bone marrow transplantation is a complex process and prognosis may depend on a number of different risk factors. Transplantation can be considered a failure when a patient's leukemia returns (relapse) or when he or she dies while in remission (treatment related death).
Source
Klein, J.P. and Moeschberger, M.L., 2003. Survival analysis: techniques for censored and truncated data (Vol. 1230). New York: Springer.
References
see also
Copelan,Biggs, Thompson, et al, Treatment for Acute Myelocytic Leukemia With Allogeneic Bone Marrow Transplantation Following Preparation With BuCy2, Blood, Volume 78, Issue 3, 1991, Pages 838-843, ISSN 0006-4971,
and
Examples
data(BMT, package = "R4HCR")