calc_concentration_response {GeoTox} | R Documentation |
Calculate the mixture response from one of three different approaches: IA, GCA, or Hazard Quotient
Description
Calculate the combined response of multiple chemicals. It calculates the generalized concentration addition response, the independent action response, and a hazard quotient
Usage
calc_concentration_response(
C_invitro,
hill_params,
max_mult = 1.5,
fixed = FALSE
)
Arguments
C_invitro |
in vitro concentrations |
hill_params |
output from |
max_mult |
upper bound multiplier for max response |
fixed |
if TRUE, sd = 0 |
Value
list of data frames
Examples
C_invitro <- list(
matrix(1:8 / 1e3, ncol = 2, dimnames = list(NULL, c("c1", "c2"))),
matrix(9:16 / 1e3, ncol = 2, dimnames = list(NULL, c("c1", "c2")))
)
hill_params <- fit_hill(
data.frame(chem = rep(c("c1", "c2"), each = 3),
logc = c(-1, 0, 1, 0, 1, 2),
resp = c(10, 5, 0, 4, 2, 0) / 10),
chem = "chem"
)
calc_concentration_response(C_invitro, hill_params)
calc_concentration_response(C_invitro, hill_params, fixed = TRUE)
[Package GeoTox version 0.2.0 Index]