%global __brp_check_rpaths %{nil} %global __requires_exclude ^libmpi %global packname AllelicSeries %global packver 0.1.1.2 %global rlibdir /usr/local/lib/R/library Name: R-CRAN-%{packname} Version: 0.1.1.2 Release: 1%{?dist}%{?buildtag} Summary: Allelic Series Test License: BSD_3_clause + file LICENSE URL: https://cran.r-project.org/package=%{packname} Source0: %{url}&version=%{packver}#/%{packname}_%{packver}.tar.gz BuildRequires: R-devel Requires: R-core BuildRequires: R-CRAN-CompQuadForm BuildRequires: R-CRAN-glue BuildRequires: R-methods BuildRequires: R-CRAN-Rcpp BuildRequires: R-CRAN-RNOmni BuildRequires: R-CRAN-SKAT BuildRequires: R-CRAN-RcppArmadillo Requires: R-CRAN-CompQuadForm Requires: R-CRAN-glue Requires: R-methods Requires: R-CRAN-Rcpp Requires: R-CRAN-RNOmni Requires: R-CRAN-SKAT %description Implementation of gene-level rare variant association tests targeting allelic series: genes where increasingly deleterious mutations have increasingly large phenotypic effects. The COding-variant Allelic Series Test (COAST) operates on the benign missense variants (BMVs), deleterious missense variants (DMVs), and protein truncating variants (PTVs) within a gene. COAST uses a set of adjustable weights that tailor the test towards rejecting the null hypothesis for genes where the average magnitude of effect increases monotonically from BMVs to DMVs to PTVs. See McCaw ZR, O’Dushlaine C, Somineni H, Bereket M, Klein C, Karaletsos T, Casale FP, Koller D, Soare TW. (2023) "An allelic series rare variant association test for candidate gene discovery" . %prep %setup -q -c -n %{packname} # fix end of executable files find -type f -executable -exec grep -Iq . {} \; -exec sed -i -e '$a\' {} \; # prevent binary stripping [ -d %{packname}/src ] && find %{packname}/src -type f -exec \ sed -i 's@/usr/bin/strip@/usr/bin/true@g' {} \; || true [ -d %{packname}/src ] && find %{packname}/src/Make* -type f -exec \ sed -i 's@-g0@@g' {} \; || true # don't allow local prefix in executable scripts find -type f -executable -exec sed -Ei 's@#!( )*/usr/local/bin@#!/usr/bin@g' {} \; %build %install mkdir -p %{buildroot}%{rlibdir} %{_bindir}/R CMD INSTALL -l %{buildroot}%{rlibdir} %{packname} test -d %{packname}/src && (cd %{packname}/src; rm -f *.o *.so) rm -f %{buildroot}%{rlibdir}/R.css # remove buildroot from installed files find %{buildroot}%{rlibdir} -type f -exec sed -i "s@%{buildroot}@@g" {} \; %files %{rlibdir}/%{packname}