%global __brp_check_rpaths %{nil} %global __requires_exclude ^libmpi %global packname FastSurvival %global packver 1.0.0 %global rlibdir /usr/local/lib/R/library Name: R-CRAN-%{packname} Version: 1.0.0 Release: 1%{?dist}%{?buildtag} Summary: Fast Survival Analysis and Simulation for Clinical Trials License: MIT + file LICENSE URL: https://cran.r-project.org/package=%{packname} Source0: %{url}&version=%{packver}#/%{packname}_%{packver}.tar.gz BuildRequires: R-devel >= 4.1.0 Requires: R-core >= 4.1.0 BuildRequires: R-graphics BuildRequires: R-grDevices BuildRequires: R-stats BuildRequires: R-CRAN-dqrng BuildRequires: R-CRAN-Rcpp BuildRequires: R-CRAN-mvtnorm Requires: R-graphics Requires: R-grDevices Requires: R-stats Requires: R-CRAN-dqrng Requires: R-CRAN-Rcpp Requires: R-CRAN-mvtnorm %description Provides fast alternatives to standard survival analysis functions in the 'survival' package, together with tools for time-to-event trial simulation and sequential analysis. The estimation and testing functions cover a single-time-point Kaplan-Meier estimator (survfit_fast()), log-rank tests including weighted and stratified variants (survdiff_fast()), a closed-form hazard ratio estimator based on the Pike-Halley Estimator method (coxph_fast()), restricted mean survival time (rmst_fast()), window mean survival time (wmst_fast()), milestone survival comparison (milestone_fast()), median survival time (medsurv_fast()), the max-combo test (maxcombo_fast()), the robust modestly-weighted log-rank test (rmw_fast()), the weighted Kaplan-Meier (Pepe-Fleming) test (wkm_fast()), the average hazard with survival weight (ahsw_fast()), and the Kalbfleisch-Prentice average hazard ratio (ahr_fast()). The simulation layer generates individual patient data (simdata_fast()), performs interim or sequential analyses (analysis_fast()), and aggregates operating characteristics (simsummary_fast()). A visualization layer assembles design-stage scenarios (gen_scenario_fast()) and builds analysis-stage Kaplan-Meier curves (kmcurve_fast()), each with plot and print methods. All functions are designed for repeated evaluation inside large simulation loops, such as adaptive sample-size re-estimation, probability-of-success calculations, and regional consistency evaluation in multi-regional trials. Core computations are implemented in 'C++' via 'Rcpp' for maximum performance. Methodological background is described in Collett (2014, ISBN:9780429196294). %prep %setup -q -c -n %{packname} # fix end of executable files find -type f -executable -exec grep -Iq . {} \; -exec sed -i -e '$a\' {} \; # prevent binary stripping [ -d %{packname}/src ] && find %{packname}/src -type f -exec \ sed -i 's@/usr/bin/strip@/usr/bin/true@g' {} \; || true [ -d %{packname}/src ] && find %{packname}/src/Make* -type f -exec \ sed -i 's@-g0@@g' {} \; || true # don't allow local prefix in executable scripts find -type f -executable -exec sed -Ei 's@#!( )*/usr/local/bin@#!/usr/bin@g' {} \; %build %install mkdir -p %{buildroot}%{rlibdir} %{_bindir}/R CMD INSTALL -l %{buildroot}%{rlibdir} %{packname} test -d %{packname}/src && (cd %{packname}/src; rm -f *.o *.so) rm -f %{buildroot}%{rlibdir}/R.css # remove buildroot from installed files find %{buildroot}%{rlibdir} -type f -exec sed -i "s@%{buildroot}@@g" {} \; %files %{rlibdir}/%{packname}