Glucose {R4HCR} | R Documentation |
Comparison of impedance to insulin-mediated glucose uptake
Description
Data from the study by Shen et al 'Comparison of impedance to insulin-mediated glucose uptake in normal subjects and in subjects with latent diabetes.
Usage
Glucose
Format
A data frame with 14 observations on the following 3 variables.
diabetes
Indicator of whether the person had diabetes (
1
) or not (0
).glucose
Weighted glucose response to an oral glucose tolerance test (mg/100ml).
impedance
Glucose Impedance (ohms).
Details
These data are originally from Shen et al (1970) and reprinted in Hollander et al (2013). Glucose impedance represents the tissues' insensitivity or resistance to insulin-mediated glucose uptake. It was hypothesised that the newly developed technique of estimating impedance would allow the detection of a difference in glucose uptake efficiency between normal and mildly diabetic subjects. Two groups of normal-weight subjects were studied, one had maturity onset latent diabetes, and the other (matched for age, weight, and percent adiposity) were 'normal'. Impedance data is taken from Table II 'Results of Standard Infusion Studies', whereas the glucose response data is shown in Table 1.
Source
Shen SW, Reaven GM, Farquhar JW. Comparison of impedance to insulin-mediated glucose uptake in normal subjects and in subjects with latent diabetes. J Clin Invest. 1970 Dec;49(12):2151-60. doi: 10.1172/JCI106433. PMID: 5480843; PMCID: PMC322715.
References
Shen SW, Reaven GM, Farquhar JW. Comparison of impedance to insulin-mediated glucose uptake in normal subjects and in subjects with latent diabetes. J Clin Invest. 1970 Dec;49(12):2151-60. doi: 10.1172/JCI106433. PMID: 5480843; PMCID: PMC322715.
Hollander, M., Wolfe, D.A. and Chicken, E., 2013. Nonparametric statistical methods. John Wiley & Sons.
Examples
data(Glucose, package = "R4HCR")
# Kendall's Tau.
with(
subset(Glucose, diabetes==0),
cor.test(glucose, impedance,
exact = TRUE,
method = "kendall")
)