COMP {wintime} | R Documentation |
Run composite analysis
Description
This function fits a Cox Model to time-to-event data and calculates the z statistic. In the wintime package, this function is used for the EWTR-composite max test (MAX) method.
Usage
COMP(n, Time, Delta, cov, trt)
Arguments
n |
The total number of trial participants. |
Time |
A m x n matrix of event times (days), where m is the number of events in the hierarchy. Rows should represent events and columns should represent participants. Event rows should be in increasing order of clinical severity. |
Delta |
A m x n matrix of event indicators, where m is the number of events in the hierarchy. Rows should represent events and columns should represent participants. Event rows should be in increasing order of clinical severity. |
cov |
A n x p matrix of covariate values, where p is the number of covariates. Rows should represent participants and columns should represent covariate values. |
trt |
A vector of length n containing treatment arm indicators (1 for treatment, 0 for control). |
Value
The z-statistic of the treatment effect from the Cox Model fit.