Xu2018 {poth} | R Documentation |
Safety of Immune Checkpoint Inhibitors in Cancer
Description
Data from a network meta-analysis on immune checkpoint inhibitors (ICIs) to assess the safety of ICI drugs as cancer treatment (Xu et al., 2018).
Format
A data frame with the following columns:
studyID | study id |
treatment | treatment name |
adverse | number of adverse events |
n | group sample size |
Details
Data were obtained from Rosenberger et al. (2021), who re-analysed the data. There are seven treatments and 23 studies. The outcome of interest is the number of treatment-related adverse events, so smaller values indicate a safer treatment.
Source
Rosenberger, K.J., Duan, R., Chen, Y. et al. (2021): Predictive P-score for treatment ranking in Bayesian network meta-analysis. BMC Med Res Methodol 21, 213. doi:10.1186/s12874-021-01397-5
See Also
Examples
data(Xu2018)
head(Xu2018)
library("netmeta")
pw <- pairwise(treat = treatment, event = adverse, n = n,
studlab = studyID, data = Xu2018, sm = "OR")
#
net <- netmeta(pw, small.values = "desirable", method.tau = "REML",
common = FALSE)
#
poth(net)
[Package poth version 0.2-0 Index]