%global __brp_check_rpaths %{nil} %global __requires_exclude ^libmpi %global packname SlimR %global packver 1.1.3 %global rlibdir /usr/local/lib/R/library Name: R-CRAN-%{packname} Version: 1.1.3 Release: 1%{?dist}%{?buildtag} Summary: Adaptive Machine Learning-Powered, Context-Matching Tool for Single-Cell and Spatial Transcriptomics Annotation License: MIT + file LICENSE URL: https://cran.r-project.org/package=%{packname} Source0: %{url}&version=%{packver}#/%{packname}_%{packver}.tar.gz BuildRequires: R-devel >= 3.5 Requires: R-core >= 3.5 BuildArch: noarch BuildRequires: R-CRAN-cowplot BuildRequires: R-CRAN-dplyr BuildRequires: R-CRAN-ggplot2 BuildRequires: R-CRAN-patchwork BuildRequires: R-CRAN-pheatmap BuildRequires: R-CRAN-readxl BuildRequires: R-CRAN-scales BuildRequires: R-CRAN-Seurat BuildRequires: R-CRAN-tidyr BuildRequires: R-tools BuildRequires: R-CRAN-tibble Requires: R-CRAN-cowplot Requires: R-CRAN-dplyr Requires: R-CRAN-ggplot2 Requires: R-CRAN-patchwork Requires: R-CRAN-pheatmap Requires: R-CRAN-readxl Requires: R-CRAN-scales Requires: R-CRAN-Seurat Requires: R-CRAN-tidyr Requires: R-tools Requires: R-CRAN-tibble %description Annotates single-cell and spatial-transcriptomic (ST) data using context-matching marker datasets. It creates a unified marker list (`Markers_list`) from multiple sources: built-in curated databases ('Cellmarker2', 'PanglaoDB', 'ScType', 'scIBD', 'TCellSI', 'PCTIT', 'PCTAM'), Seurat objects with cell labels, or user-provided Excel tables. SlimR first uses adaptive machine learning for parameter optimization, and then offers two automated annotation approaches: 'cluster-based' and 'per-cell'. Cluster-based annotation assigns one label per cluster, expression-based probability calculation, and AUC validation. Per-cell annotation assigns labels to individual cells using three scoring methods with adaptive thresholds and ratio-based confidence filtering, plus optional UMAP spatial smoothing, making it ideal for heterogeneous clusters and rare cell types. The package also supports semi-automated workflows with heatmaps, feature plots, and combined visualizations for manual annotation. For more information, see the package documentation at . %prep %setup -q -c -n %{packname} # fix end of executable files find -type f -executable -exec grep -Iq . {} \; -exec sed -i -e '$a\' {} \; # prevent binary stripping [ -d %{packname}/src ] && find %{packname}/src -type f -exec \ sed -i 's@/usr/bin/strip@/usr/bin/true@g' {} \; || true [ -d %{packname}/src ] && find %{packname}/src/Make* -type f -exec \ sed -i 's@-g0@@g' {} \; || true # don't allow local prefix in executable scripts find -type f -executable -exec sed -Ei 's@#!( )*/usr/local/bin@#!/usr/bin@g' {} \; %build %install mkdir -p %{buildroot}%{rlibdir} %{_bindir}/R CMD INSTALL -l %{buildroot}%{rlibdir} %{packname} test -d %{packname}/src && (cd %{packname}/src; rm -f *.o *.so) rm -f %{buildroot}%{rlibdir}/R.css # remove buildroot from installed files find %{buildroot}%{rlibdir} -type f -exec sed -i "s@%{buildroot}@@g" {} \; %files %{rlibdir}/%{packname}