%global __brp_check_rpaths %{nil} %global __requires_exclude ^libmpi %global packname twoPhaseGAS %global packver 1.2.5 %global rlibdir /usr/local/lib/R/library Name: R-CRAN-%{packname} Version: 1.2.5 Release: 1%{?dist}%{?buildtag} Summary: Two-Phase Genetic Association Study Design and Analysis with Missing Covariates by Design License: GPL (>= 2) URL: https://cran.r-project.org/package=%{packname} Source0: %{url}&version=%{packver}#/%{packname}_%{packver}.tar.gz BuildRequires: R-devel >= 3.5.0 Requires: R-core >= 3.5.0 BuildArch: noarch BuildRequires: R-CRAN-kofnGA >= 1.2 BuildRequires: R-CRAN-data.table BuildRequires: R-CRAN-dfoptim BuildRequires: R-CRAN-enrichwith BuildRequires: R-CRAN-MASS BuildRequires: R-CRAN-Matrix BuildRequires: R-CRAN-nloptr BuildRequires: R-parallel BuildRequires: R-stats BuildRequires: R-utils Requires: R-CRAN-kofnGA >= 1.2 Requires: R-CRAN-data.table Requires: R-CRAN-dfoptim Requires: R-CRAN-enrichwith Requires: R-CRAN-MASS Requires: R-CRAN-Matrix Requires: R-CRAN-nloptr Requires: R-parallel Requires: R-stats Requires: R-utils %description Provides functionality for designing and analysing two-phase genetic association studies. Phase 1 data usually come from genome-wide association study (GWAS) results and we assume phase 2 data will be part of a targeted genome sequencing or fine-mapping study. At design stage, the package assists in selecting a subset of individuals that will be sequenced for phase 2 via alternative approaches, including a flexible genetic algorithm (GA) for near-optimal designs. Once phase 2 data have been collected, the package implements methods to analyse phase 1 and phase 2 data together using semi-parametric regression models via the expectation-maximization (EM) algorithm. For more details see Espin-Garcia, Craiu and Bull (2018) and Espin-Garcia, Craiu and Bull (2021) . %prep %setup -q -c -n %{packname} # fix end of executable files find -type f -executable -exec grep -Iq . {} \; -exec sed -i -e '$a\' {} \; # prevent binary stripping [ -d %{packname}/src ] && find %{packname}/src -type f -exec \ sed -i 's@/usr/bin/strip@/usr/bin/true@g' {} \; || true [ -d %{packname}/src ] && find %{packname}/src/Make* -type f -exec \ sed -i 's@-g0@@g' {} \; || true # don't allow local prefix in executable scripts find -type f -executable -exec sed -Ei 's@#!( )*/usr/local/bin@#!/usr/bin@g' {} \; %build %install mkdir -p %{buildroot}%{rlibdir} %{_bindir}/R CMD INSTALL -l %{buildroot}%{rlibdir} %{packname} test -d %{packname}/src && (cd %{packname}/src; rm -f *.o *.so) rm -f %{buildroot}%{rlibdir}/R.css # remove buildroot from installed files find %{buildroot}%{rlibdir} -type f -exec sed -i "s@%{buildroot}@@g" {} \; %files %{rlibdir}/%{packname}